Calcitonin Salmon Nasal Solution is useful in treating post menopausal osteoporosis, high calcium level in the blood, hypercalcemia and paget’s disease. Calcitonin is a receptor agonist that acts by suppressing the activity of osteoclasts, cells which cause destruction of the bone, thereby strengthening the bones and minimizing the risk of fractures. The spray contains a thyroid hormone that naturally regulates the body's calcium levels.